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(now part of Dexorgen Inc., Rockville, MD, USA), with their proprietary protocol adapted from published literature 18,19,20,21

While current therapy of diabetes has targeted glucose control, treatment of diabetic complications, for example, neuropathy, aside from striving for good metabolic control has been only symptomatic

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One area that remains contentious in skin biology, as in other tissues, is the extent to which estrogen replacement can reverse detrimental changes that have already occurred and whether estrogen is beneficial in skin that is decades post menopause rather than in the perimenopause period